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All Clinical Trials

Displaying results 1-10 of 3532

NCT01874236

VaReFi Validity and Reliability of Diagnostic Findings of SI Joint Blocking

TERMINATED

SI Joint Pain

The purpose of the trial is to confirm the validity and reliability of diagnostic SI joint blocks.

SI-BONE, Inc.

NCT05252702

Aveir Dual-Chamber Leadless i2i IDE Study

ACTIVE_NOT_RECRUITING

Cardiac Pacemaker, Artificial

Cardiac Rhythm Disorder

Bradycardia

Prospective, non-randomized, multi-center, international study designed to evaluate the safety and effectiveness of the Aveir™ Dual-Chamber (DR) Leadless Pacemaker system.

Abbott Medical Devices

NCT03010995

The Acute Cardiovascular Effects of Nicotine in E-cigarettes (ACE) Study

WITHDRAWN

Cigarette Smoking Toxicity

Nicotine

Acute Cardiovascular Disease

The goal of this project is to evaluate the nicotine induced acute cardiovascular changes in E-Cigarette users and also study the mechanism involved particularly with vascular impairment.

University of Louisville

NCT05740566

A Randomized, Open-label, Phase 3 Study of Tarlatamab Compared With Standard of Care in Subjects With Relapsed Small Cell Lung Cancer After Platinum-based First-line Chemotherapy

ACTIVE_NOT_RECRUITING

Small Cell Lung Cancer (SCLC)

The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).

Amgen

NCT01829477

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, 24-Week Study to Evaluate the Efficacy and Safety of Daily Oral TAK-875 50 mg Compared With Placebo as an Add-on to Glimepiride in Subjects With Type 2 Diabetes

TERMINATED

Diabetes Mellitus, Type 2

The purpose of this study is to evaluate the effect of TAK-875 compared to placebo on glycemic control over a 24-week Treatment Period when used as an add-on to glimepiride in addition to diet and exercise.

Takeda

NCT03627091

A Phase 3 Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Study of SHP647 as Maintenance Therapy in Subjects With Moderate to Severe Crohn's Disease (CARMEN CD 307)

TERMINATED

Crohn's Disease

The purpose of this study is to evaluate the efficacy and safety of ontamalimab as maintenance treatment in participants with moderate to severe Crohn's disease (CD).

Takeda

NCT03734536

Prospective Multi-center Study Comparing REGENETEN in Lieu of Standard Arthroscopic Repair of High-grade (>50%) Partial-thickness Tears

TERMINATED

Arthroscopic Surgical Treatment of High-grade (>50%) Partialthickness

The goal of this clinical trial is to demonstrate that REGENETEN is superior to standard repair techniques when surgically treating high-grade (\>50%) partial-thickness tears.

Smith & Nephew, Inc.

NCT04133636

A Phase 2, Multicohort Open-Label Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against BCMA in Subjects With Multiple Myeloma

RECRUITING

Multiple Myeloma

The purpose of this study is to evaluate the overall minimal residual disease (MRD) negative rate of participants who receive JNJ-68284528.

Janssen Research & Development, LLC

NCT04830124

A Phase 2, Open-Label, Multicenter, Cohort Study of Nemvaleukin Alfa (ALKS 4230) Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous Melanoma or Advanced Mucosal Melanoma - ARTISTRY-6

TERMINATED

Cutaneous Melanoma

Mucosal Melanoma

This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma

Mural Oncology, Inc

NCT05995405

Safety and Tolerability of GTX-104 (Nimodipine Injection for IV Infusion) Compared with Oral Nimodipine in Patients Hospitalized for Aneurysmal Subarachnoid Hemorrhage (aSAH): a Prospective, Randomized Trial

ACTIVE_NOT_RECRUITING

Aneurysmal Subarachnoid Hemorrhage (aSAH)

The purpose of this study is to deliver nimodipine via IV directly into the bloodstream and to determine if this is as safe and tolerable as oral nimodipine capsules.

Grace Therapeutics Inc.

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